GPR40 agonist 4

GPR40 agonist 4 is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54.

Product Specifications

CAS Number

[2102196-57-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/FAA1_agonist-1.html

Concentration

10mM

Purity

98.38

Solubility

DMSO : 160 mg/mL (ultrasonic; warming)

Smiles

ClC1=CC=CC=C1C2=CC(COC3=CC=C(S(CC(O)=O)(=O)=O)C=C3)=CC=C2

Molecular Formula

C21H17ClO5S

Molecular Weight

416.87

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Li Z, et al. Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes. Eur J Med Chem. 2017 Sep 29;138:458-479.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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