AGN 192836

AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.

Adrenergic Receptor

Reference compound

GPCR/G Protein;Neuronal Signaling

Metabolism-protein/nucleotide metabolism

Cardiovascular Disease; Endocrinology

https://www.medchemexpress.com/AGN_192836.html

99.49

DMSO : 80 mg/mL (ultrasonic)

CC1=C2OCCOC2=CC=C1NC3=NC=CN3

231.25

[1]Stephen M, et al. Synthesis and Evaluation of 2-(Arylamino)imidazoles as α2-Adrenergic Agonists. J. Med. Chem., 1997, 40 (1), pp 18–23

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-100300/AGN-192836-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-100300/AGN-192836-SDS-MedChemExpress.pdf

No Development Reported

171102-29-7