AGN 192836
AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.
Product Specifications
CAS Number
[171102-29-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/AGN_192836.html
Purity
99.49
Solubility
DMSO : 80 mg/mL (ultrasonic)
Smiles
CC1=C2OCCOC2=CC=C1NC3=NC=CN3
Molecular Formula
C12H13N3O2
Molecular Weight
231.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Stephen M, et al. Synthesis and Evaluation of 2- (Arylamino) imidazoles as α2-Adrenergic Agonists. J. Med. Chem., 1997, 40 (1), pp 18–23
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α adrenergic receptor
Available Sizes
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ACTL6A (Actin-like Protein 6A, 53kD BRG1-associated Factor A, Actin-related Protein Baf53a, ArpNbeta, BRG1-associated Factor 53A, BAF53A) APC
ACTL6A (Actin-like Protein 6A, 53kD BRG1-associated Factor A, Actin-related Protein Baf53a, ArpNbeta, BRG1-associated Factor 53A, BAF53A) APC
