AGN 192836

AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively.

Product Specifications

CAS Number

[171102-29-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/AGN_192836.html

Purity

99.49

Solubility

DMSO : 80 mg/mL (ultrasonic)

Smiles

CC1=C2OCCOC2=CC=C1NC3=NC=CN3

Molecular Formula

C12H13N3O2

Molecular Weight

231.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Stephen M, et al. Synthesis and Evaluation of 2- (Arylamino) imidazoles as α2-Adrenergic Agonists. J. Med. Chem., 1997, 40 (1), pp 18–23

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α adrenergic receptor

Available Sizes

Curated Selection

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