Indian Hedgehog Protein (Human Recombinant)

<strong>Indian hedgehog protein</strong>_x000D_ <strong>Catalog number:</strong> B2010367_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Indian hedgehog protein expressed in E. coli. This protein acts as protein is involved in chondrocyte differentiation, proliferation and maturation especially during endochondral ossification._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuIHH; HHG-2_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Deng A, Zhang H, Hu M, Liu S, Gao Q, Wang Y, Guo C. Knockdown of Indian_x000D_ hedgehog protein induces an inhibition of cell growth and differentiation in_x000D_ osteoblast MC3T3‑E1 cells. Mol Med Rep. 2017 Dec;16(6):7987-7992._x000D_ _x000D_ 2: Plubell DL, Fenton AM, Rosario S, Bergstrom P, Wilmarth PA, Clark WM, Zakai_x000D_ NA, Quinn JF, Minnier J, Alkayed NJ, Fazio S, Pamir N. High-Density Lipoprotein_x000D_ Carries Markers That Track With Recovery From Stroke. Circ Res. 2020 Oct_x000D_ 23;127(10):1274-1287._x000D_ _x000D_ 3: Smith K, Alnifaidy R, Wei Q, Nieman LK. Endometrial Indian hedgehog_x000D_ expression is decreased in women with endometriosis. Fertil Steril. 2011 Jun_x000D_ 30;95(8):2738-41.e1-3._x000D_ _x000D_ 4: Sieker JT, Kunz M, Weißenberger M, Gilbert F, Frey S, Rudert M, Steinert AF._x000D_ Direct bone morphogenetic protein 2 and Indian hedgehog gene transfer for_x000D_ articular cartilage repair using bone marrow coagulates. Osteoarthritis_x000D_ Cartilage. 2015 Mar;23(3):433-42._x000D_ _x000D_ 5: Kim SY, Im GI. The expressions of the SOX trio, PTHrP (parathyroid hormone-_x000D_ related peptide)/IHH (Indian hedgehog protein) in surgically induced_x000D_ osteoarthritis of the rat. Cell Biol Int. 2011 May;35(5):529-35._x000D_ _x000D_ 6: Parra S, Heras M, Herrero P, Amigó N, Garcés E, Girona J, Correig X, Canela_x000D_ N, Castro A. Gelsolin: a new biomarker of disease activity in SLE patients_x000D_ associated with HDL-c. Rheumatology (Oxford). 2020 Mar 1;59(3):650-661._x000D_ _x000D_ 7: Yang L, Gee AO, Zielinska-Kwiatkowska A, Chansky HA. Generation and_x000D_ characterization of mice with mesenchyme-specific deletion of the entire ESET_x000D_ histone methyltransferase protein. Genesis. 2018 Feb;56(2)._x000D_ _x000D_ 8: Hussain MZ, Talapaneni AK, Prasad M, Krishnan R. Serum PTHrP level as a_x000D_ biomarker in assessing skeletal maturation during circumpubertal development. Am_x000D_ J Orthod Dentofacial Orthop. 2013 Apr;143(4):515-21._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23929766/">9: Kim HK, Feng GS, Chen D, King PD, Kamiya N. Targeted disruption of Shp2 in_x000D_ chondrocytes leads to metachondromatosis with multiple cartilaginous_x000D_ protrusions. J Bone Miner Res. 2014 Mar;29(3):761-9. </a>_x000D_ _x000D_ <strong>Products Related to Indian hedgehog protein </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>