WZB117
WZB117 is a glucose transporter 1 (Glut1) inhibitor, which downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo.
Product Specifications
CAS Number
[1223397-11-2]
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H412
Target
GLUT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/WZB117.html
Purity
99.93
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
OC1=CC=CC(C(OC2=CC=CC(F)=C2OC(C3=CC(O)=CC=C3)=O)=O)=C1
Molecular Formula
C20H13FO6
Molecular Weight
368.31
Precautions
H315, H319, H335, H412
References & Citations
[1]Liu Y, et al. A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo. Mol Cancer Ther. 2012 Aug;11 (8) :1672-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GLUT1
Available Sizes
Curated Selection
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