L-158809
L-158809 is an angiotensin type 1 (AT1) receptor antagonist that prevents or ameliorates fractionated whole-brain irradiation-induced cognitive impairment. L-158809 is promising for research of brain tumor[1].
Product Specifications
CAS Number
133240-46-7
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/l-158809.html
Smiles
CCC1=NC2=C(C)C=C(C)N=C2N1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5
Molecular Formula
C24H23N7
Molecular Weight
409.49
References & Citations
[1]Robbins ME, et al. The AT1 receptor antagonist, L-158,809, prevents or ameliorates fractionated whole-brain irradiation-induced cognitive impairment. Int J Radiat Oncol Biol Phys. 2009 Feb 1;73 (2) :499-505.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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