H-2kd/H-2D mAb (34-1-2S), InVivoPure+
The anti-H2Kd/H-2Dd monoclonal antibody (clone 34-1-2S) is a mouse-derived antibody that targets MHC class I alloantigens, specifically H-2Kd and H-2Dd. These antigens are expressed on the surface of nucleated cells in mice with the H-2Kd/H-2Dd haplotype. The antibody is critical for antigen presentation to T cells expressing CD3/TCR and CD8 proteins. This antibody is known for its cross-reactivity with other MHC class I alloantigens, including those of the H-2Kb, H-2Ks, H-2Kr, H-2Kq, and H-2Kp haplotypes. It is commonly used in flow cytometry for the analysis of mouse splenocytes and other cell types. This antibody is a valuable tool for researchers studying immune responses by helping to identify and characterize cells based on their MHC class I expression.
Product Specifications
Product Name Alternative
UniProt
Q31295
Reactivity
Mouse
Immunogen
Animals were immunized with spleen cells from BDF1 mice
Target
H-2kd/H-2D, cross react with Kb, s, r, q, p
Clonality
Monoclonal
Clone
34-1-2S
Conjugation
Unconjugated
Concentration
≥ 1 mg/ mL
Purity
≥ 95 % (CGE, reducing conditions) ≤ 10 % aggregates (analytical SEC) Endotoxin level ≤ 1 EU/mg
Form
Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Recomended Isotype: Mouse IgG2A k Isotype Control, Recomended Isotype Catalog: orb2568793
Host or Source
Mouse
Isotype
M IgG2a
Available Sizes
Frequently Asked Questions
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