Recombinant Mouse NT-ProBNP Protein (Trx Tag)
Product Specifications
Background
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Abbreviation
NT-ProBNP
Synonyms
B-Type Natriuretic Peptide; GC-B; Natriuretic Peptide Precursor B; NT-Pro-BNP; Nppb
UniProt
P40753
Accession Number
P40753
Expression System
E.coli
Tag
N-Trx
Sequence
Ser26-Arg76
Field of Research
Cardiovascular; Signal Transduction; Tags and Cell Markers; Cell Biology
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
25.6 kDa
Observed Molecular Weight
22 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Mouse
Available Sizes
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