Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Canine GITR / TNFRSF18 Protein, His Tag

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Product Specifications

Background

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 20-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

D7F619-1

Expression Region

Gly 23 - Pro 154

Host

HEK293

Target

GITR

Conjugation

Unconjugated

Tag

C-10xHis

Source

Canine

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Canine GITR, His Tag (Cat. No. GIR-C52H6) at 2 μg/mL (100 μL/well) can bind Human GITR Ligand, Fc Tag (Cat. No. GIL-H526a) with a linear range of 2-40 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

15.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

HEK293

Species

Canine

Protein ID

D7F619-1

Preservative

Trehalose

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

macroH2A.1 Rabbit Polyclonal Antibody
ER1803-04 100 µL

macroH2A.1 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Human FRRS1 activation kit by CRISPRa
GA118194 1 Kit

Human FRRS1 activation kit by CRISPRa

Sign In for Pricing
View Details
Aspergillus Mouse Monoclonal Antibody [Clone ID: WF-AF-1]
AM05894PU-N 250 µg

Aspergillus Mouse Monoclonal Antibody [Clone ID: WF-AF-1]

Sign In for Pricing
View Details
SS18 (NM_001007559) Human Over-expression Lysate
LY423511 100 µg

SS18 (NM_001007559) Human Over-expression Lysate

Sign In for Pricing
View Details
1’-Hydroxy Bufuralol (Mixture of Diastereomers)
TRC-H830480-10MG 10 mg

1’-Hydroxy Bufuralol (Mixture of Diastereomers)

Sign In for Pricing
View Details
ARHGEF7 (NM_001113513) Human Recombinant Protein
TP326057 20 µg

ARHGEF7 (NM_001113513) Human Recombinant Protein

Sign In for Pricing
View Details