AL-611
AL-611 is an HCV NS5B polymerase inhibitor (EC50 = 5 nM) .
Product Specifications
CAS Number
2481279-61-0
UNSPSC
12352005
Target
HCV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/al-611.html
Purity
99.93
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
C[C@@]1([C@](O[C@@](F)([C@H]1O)CO[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)([H])N3C4=NC(N)=NC(OCC)=C4N=C3)F
Molecular Formula
C25H33F2N6O8P
Molecular Weight
614.54
References & Citations
[1]Wang G, et al. Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of AL-611 as an HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C. J Med Chem. 2020 Sep 24;63 (18) :10380-10395.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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