Tyk2 (phospho-Tyr1054/1055) rabbit pAb
Tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II Cytokine receptors and promulgate Cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
UniProt
P29597
Swiss Prot
P29597
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phosho peptide around human Tyk2 (Tyr1054 and 1055)
Target
Tyk2
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Buffer
-20°C/1 year
Molecular Weight
134kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
134kD
Fragment
IgG
Subcellular Location
Nucleus, cytoplasm, cytosol, cytoskeleton, membrane, extrinsic component of cytoplasmic side of plasma membrane, extracellular exosome
Other Product Names
Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
Gene ID (Human)
7297
Available Sizes
Frequently Asked Questions
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