Nelremagpran

MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 [1].

Product Specifications

CAS Number

[2492595-24-9]

Product Name Alternative

MRGPRX4 modulator-2

UNSPSC

12352005

Target

Mas-related G-protein-coupled Receptor (MRGPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mrgprx4-modulator-2.html

Purity

99.94

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O)C1=CC=CC(COC2=CC=C(C(F)(F)F)C=C2Cl)=C1F

Molecular Formula

C15H9ClF4O3

Molecular Weight

348.68

References & Citations

[1]Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55)

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

NBP3-08515G 100 µL

Mouse Monoclonal Collagen IV Antibody (M3F7) [DyLight 488]

View Details

MF-0128585-01 10 mg

Mannosamine-biotin adduct

View Details

MF-0128585-02 50 mg

Mannosamine-biotin adduct

View Details

MBS7041546-01 0.02 mg

Recombinant Zea mays CASP-like protein 1

View Details

MBS7041546-02 0.1 mg

Recombinant Zea mays CASP-like protein 1

View Details

MBS7041546-03 5x 0.1 mg

Recombinant Zea mays CASP-like protein 1

View Details