Nelremagpran
MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 [1].
Product Specifications
CAS Number
[2492595-24-9]
Product Name Alternative
MRGPRX4 modulator-2
UNSPSC
12352005
Target
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrgprx4-modulator-2.html
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC=CC(COC2=CC=C(C(F)(F)F)C=C2Cl)=C1F
Molecular Formula
C15H9ClF4O3
Molecular Weight
348.68
References & Citations
[1]Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55)
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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