Tropisetron (Hydrochloride)
Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChRreceptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab -induced hippocampal neuroinflammation[1][2][3][4].
Product Specifications
CAS Number
105826-92-4
Product Name Alternative
SDZ-ICS-930
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
5-HT Receptor; nAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Tropisetron-Hydrochloride.html
Purity
99.97
Solubility
DMSO : 70 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
O=C(C1=CNC2=C1C=CC=C2)O[C@H]3C[C@H]4CC[C@H](N4C)C3.[H]Cl
Molecular Formula
C17H21ClN2O2
Molecular Weight
320.81
Precautions
H315, H319, H320
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Lactoferrin
Citation 01
Available Sizes
Frequently Asked Questions
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