EA4
EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA2 with a Ki value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis[1].
Product Specifications
CAS Number
[389614-94-2]
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ea4.html
Purity
98.75
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C(C1=CC=C(N(CC)CC)C=C1)=C2Cl)C3=C(N=CC=C3)C2=O
Molecular Formula
C19H17ClN2O2
Molecular Weight
340.80
References & Citations
[1]Shin, Hae Sook et al. Purification and characterization of a cytosolic, 42-kDa and Ca2+-dependent phospholipase A2 from bovine red blood cells: its involvement in Ca2+-dependent release of arachidonic acid from mammalian red blood cells. The Journal of biological chemistry vol. 277,23 (2002) : 21086-94.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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