Euphornin
Euphornin is a anticaner agent, that can be isolated from E. helioscopia. Euphornin induces apoptosis via caspase-mediated pathways. Euphornin induces cell cycle arrest by increasing the level of the phospho-CDK1 (Tyr15) protein[1].
Product Specifications
CAS Number
80454-47-3
UNSPSC
12352005
Target
Apoptosis; Caspase
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/euphornin.html
Purity
98.09
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C)O[C@H]1C(C)(C)/C=C\[C@H](C)[C@H](OC(C)=O)[C@]2(O)[C@@]([C@@H](OC(C3=CC=CC=C3)=O)[C@@H](C)C2)([H])/C=C(C)/[C@H](OC(C)=O)C1
Molecular Formula
C33H44O9
Molecular Weight
584.70
References & Citations
[1]Li XQ, et al. Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest. Onco Targets Ther. 2018 Jul 27;11:4395-4405.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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