Carbazochrome (sodium sulfonate)

Carbazochrome sodium sulfonate (AC-17) is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome sodium sulfonate is an antihemorrhagic agent[1].

Product Specifications

CAS Number

[51460-26-5]

Product Name Alternative

AC-17

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/carbazochrome-sodium-sulfonate.html

Purity

98.0

Solubility

DMSO : ≥ 49 mg/mL|H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(C(CC1=C/C2=N/NC(N)=O)N(C)C1=CC2=O)(O[Na])=O

Molecular Formula

C10H11N4NaO5S

Molecular Weight

322.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Toshiaki Sendo, et al. Carbazochrome sodium sulfonate (AC-17) reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine endothelial cells. Naunyn Schmiedebergs Arch Pharmacol. 2003 Sep;368 (3) :175-80.|[2]Toshiaki Sendo, et al. Carbazochrome attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats. Eur J Pharmacol. 2002 Aug 23;450 (2) :203-8.