MAO-B-IN-8
MAO-B-IN-8 is a potent reversible MAO-B inhibitor and an inhibitor of microglial production of neuroinflammatory mediator. MAO-B-IN-8 can be used for neurodegenerative disease research[1].
Product Specifications
CAS Number
[1638956-60-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-8.html
Concentration
10mM
Purity
98.03
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=C(C(OC)=C(C=C1)/C=C2OC3=C(C\2=O)C=CC(O)=C3)OC
Molecular Formula
C18H16O6
Molecular Weight
328.32
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Ahmed H E Hassan, et al. Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :768-780.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-B
Available Sizes
Curated Selection
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