MAO-B-IN-8

MAO-B-IN-8 is a potent reversible MAO-B inhibitor and an inhibitor of microglial production of neuroinflammatory mediator. MAO-B-IN-8 can be used for neurodegenerative disease research[1].

Product Specifications

CAS Number

[1638956-60-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mao-b-in-8.html

Concentration

10mM

Purity

98.03

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC1=C(C(OC)=C(C=C1)/C=C2OC3=C(C\2=O)C=CC(O)=C3)OC

Molecular Formula

C18H16O6

Molecular Weight

328.32

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Ahmed H E Hassan, et al. Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :768-780.