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Boc-N-PEG5-C2-NHS ester

Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2055040-78-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-n-peg5-c2-nhs-ester.html

Purity

96.91

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

Molecular Formula

C22H38N2O11

Molecular Weight

506.54

Precautions

P264-P270-P280-P302+P352-P330-P362+P364-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Curated Selection

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