What is the catalog number for Eribulin?

The catalog number for Eribulin is HY-13442.

What sizes are available for Eribulin?

Eribulin is available in the following size(s): 500 µg, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Eribulin come in?

Eribulin is available in 7 different pack sizes.

Is Eribulin in stock?

Eribulin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Eribulin?

Eribulin is manufactured by QuantiMol.

What is the estimated delivery time for Eribulin?

Estimated delivery time for Eribulin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Eribulin?

The safety data sheet for Eribulin is available here: http://file.medchemexpress.com/batch_PDF/HY-13442/Eribulin-SDS-MedChemExpress.pdf.

Eribulin

Eribulin (E7389) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules.

Product Specifications

CAS Number

253128-41-5

Product Name Alternative

B1939; E7389; ER-086526

UNSPSC

12352203

Hazard Statement

H301+H311+H331, H341, H351, H361

Target

ADC Payload; Apoptosis; Microtubule/Tubulin

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/eribulin.html

Purity

99.92

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

C=C1C[C@@](CC[C@@]2(C[C@@]3([H])O4)O[C@]([C@](O[C@](C5)([H])CC6)([H])[C@@]6([H])O7)([H])[C@@]4([H])[C@]7([H])[C@@]3([H])O2)([H])O[C@@]1([H])CC[C@](C[C@@H](C)C8=C)([H])O[C@]8([H])C[C@@](O[C@H](C[C@H](O)CN)[C@@H]9OC)([H])[C@]9([H])CC5=O

Molecular Formula

C40H59NO11

Molecular Weight

729.90

Precautions

H301+H311+H331, H341, H351, H361

References & Citations

[1]Okouneva, T., et al., Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase. Mol Cancer Ther, 2008. 7 (7) : p. 2003-11.|[2]Smith, J.A., et al., Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability. Biochemistry, 2010. 49 (6) : p. 1331-7.|[3]Towle, M.J., et al., Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res, 2011. 71 (2) : p. 496-505.|[4]Watanabe K, et, al. Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo. Oncotarget. 2019 Jan 4; 10 (2) : 161-174.