BCTP
Product Specifications
UNSPSC Description
BCTP is a TRPV1 antagonist. BCTP activated at low pH showed functional antagonist activity against human TRPV1 in CHO cells (IC50=18 nM). BCTP can be used in the study of chronic pain[1].
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bctp.html
Smiles
O=C(C1=CC(C2=CC=C(C=C2)Cl)=C(N=C1N3)C(C)(C)C)NC3=S
Molecular Weight
345.85
References & Citations
[1]Culshaw A J, et al. Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain[J]. Journal of medicinal chemistry, 2006, 49(2): 471-474.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117683/BCTP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117683/
Clinical Information
No Development Reported
CAS Number
464152-46-3
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