BCTP

BCTP is a TRPV1 antagonist. BCTP activated at low pH showed functional antagonist activity against human TRPV1 in CHO cells (IC50=18 nM) . BCTP can be used in the study of chronic pain[1].

Product Specifications

CAS Number

[464152-46-3]

UNSPSC

12352005

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bctp.html

Smiles

O=C(C1=CC(C2=CC=C(C=C2)Cl)=C(N=C1N3)C(C)(C)C)NC3=S

Molecular Formula

C17H16ClN3OS

Molecular Weight

345.85

References & Citations

[1]Culshaw A J, et al. Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain[J]. Journal of medicinal chemistry, 2006, 49 (2) : 471-474.