Recombinant Human T-cell Immunoreceptor Protein

<strong>Recombinant Human T-cell Immunoreceptor Protein</strong>_x000D_ <strong>Catalog number:</strong> B2012929_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 uL_x000D_ <strong>Molecular Weight or Concentration:</strong> 26.3 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Recombinant protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Beck JD, Reidenbach D, Salomon N, Sahin U, Türeci Ö, Vormehr M, Kranz LM. mRNA therapeutics in cancer immunotherapy Mol Cancer. 2021 Apr 15;20(1):69._x000D_ 2: Ellebrecht CT, Bhoj VG, Nace A, Choi EJ, Mao X, Cho MJ, Di Zenzo G, Lanzavecchia A, Seykora JT, Cotsarelis G, Milone MC, Payne AS. Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease Science. 2016 Jul 8;353(6295):179-84._x000D_ 3: Bonnefoy N, Olive D, Vanhove B. [Next generation of anti-immune checkpoints antibodies] Med Sci (Paris). 2019 Dec;35(12):966-974._x000D_ 4: Saito M, Suzuki H, Kaneko MK, Kato Y. TgMab-2: An Anti-human T Cell Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domain Monoclonal Antibody for Immunocytochemistry Monoclon Antib Immunodiagn Immunother. 2022 Jun;41(3):157-162._x000D_ 5: Hombach A, Heuser C, Abken H. The recombinant T cell receptor strategy: insights into structure and function of recombinant immunoreceptors on the way towards an optimal receptor design for cellular immunotherapy Curr Gene Ther. 2002 May;2(2):211-26._x000D_ 6: Kawalekar O, June CH, Milone MC. Studying Immunoreceptor Signaling in Human T Cells Using Electroporation of In Vitro Transcribed mRNA Methods Mol Biol. 2017;1584:443-450._x000D_ 7: Zhang H, Zhang Y, Dong J, Zuo S, Meng G, Wu J, Wei J. Recombinant adenovirus expressing the fusion protein PD1PVR improves CD8(+) T cell-mediated antitumor efficacy with long-term tumor-specific immune surveillance in hepatocellular carcinoma Cell Oncol (Dordr). 2021 Dec;44(6):1243-1255._x000D_ 8: Hombach A, Schlimper C, Sievers E, Frank S, Schild HH, Sauerbruch T, Schmidt-Wolf IG, Abken H. A recombinant anti-carcinoembryonic antigen immunoreceptor with combined CD3zeta-CD28 signalling targets T cells from colorectal cancer patients against their tumour cells Gut. 2006 Aug;55(8):1156-64._x000D_ 9: Hombach A, Wieczarkowiecz A, Marquardt T, Heuser C, Usai L, Pohl C, Seliger B, Abken H. Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule J Immunol. 2001 Dec 1;167(11):6123-31._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11441120">10: Hombach A, Heuser C, Marquardt T, Wieczarkowiecz A, Groneck V, Pohl C, Abken H. CD4+ T cells engrafted with a recombinant immunoreceptor efficiently lyse target cells in a MHC antigen- and Fas-independent fashion J Immunol. 2001 Jul 15;167(2):1090-6. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human T-cell Immunoreceptor Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>