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GNF-8625 monopyridin-N-piperazine (hydrochloride)

Selected Variant

HY-131706A-01

Size: 5 mg

GNF-8625 monopyridin-N-piperazine hydrochloride (TRKi-2), a TRK inhibitor, which is from the patent WO 2020038415 A1[1].

Product Specifications

CAS Number

2412055-62-8

UNSPSC

12352005

Target

Trk Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gnf-8625-monopyridin-n-piperazine-hydrochloride.html

Purity

99.74

Solubility

DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

FC1=CC([C@@H]2N(C3=NN4C(C=C3)=NC=C4C5=NC(N6CCNCC6)=CC=C5)CCC2)=CC=C1.[H]Cl

Molecular Formula

C25H27ClFN7

Molecular Weight

479.98

References & Citations

[1]By Liu, Jing, et al. Preparation of tropomyosin receptor kinase degradation compounds and methods of use. WO 2020038415 A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

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