B7-1/CD80 Polyclonal Antibody
Product Specifications
Background
B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.
Abbreviation
B7-1/CD80
UniProt
P33681
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human B7-1/CD80 protein expressed by Mammalian
Target
B lymphocyte activation antigen B7; B7-1 antigen; B7-1 antigen; CD28 antigen ligand 1; CD80 antigen; CD80 antigen CD28 antigen ligand 1; CD80 molecule; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80; LAB; CTLA-4 counter-receptor B; T-lymphocyte activation antigen CD; B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7; CD80; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; CTLA-4 counter-receptor B7.1; B7-1; BB1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Immunology; Stem Cells
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:100-1:200
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Isotype
IgG
Available Sizes
Documents
Frequently Asked Questions
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