Tirasemtiv

Tirasemtiv is an activator of the fast skeletal muscle troponin complex. Tirasemtiv is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1005491-05-3]

Product Name Alternative

CK-2017357

UNSPSC

12352005

Hazard Statement

H302, H315, H320, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Tirasemtiv.html

Purity

99.90

Solubility

DMSO : 10.91 mg/mL (ultrasonic)

Smiles

O=C1N(C(CC)CC)C2=NC(C#C)=CN=C2N1

Molecular Formula

C12H14N4O

Molecular Weight

230.27

Precautions

H302, H315, H320, H335

References & Citations

[1]Hwee DT, et al. Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse model. PLoS One. 2014 May 7;9 (5) :e96921.