Sn-Glycerol 3-phosphate (lithium)

Sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP) . Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism[1][2].

Product Specifications

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sn-glycerol-3-phosphate-lithium.html

Purity

99.94

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O[C@H](CO)COP(O[Li])(O[Li])=O

Molecular Formula

C3H7Li2O6P

Molecular Weight

183.94

References & Citations

[1]Frasson D, et al. The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats. Metabolism. 2012 Oct;61 (10) :1473-85. |[2]Shen W, et al. Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis. Plant Cell. 2006 Feb;18 (2) :422-41.