Succinimide
Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent[1][2].
Product Specifications
CAS Number
123-56-8
Product Name Alternative
Pyrrolidine-2,5-dione
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Biochemical Assay Reagents
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/succinimide.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1NC(CC1)=O
Molecular Formula
C4H5NO2
Molecular Weight
99.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Chu GC, et al. Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures. Pharm Res. 2007 Jun;24 (6) :1145-56. |[2]Yan B, et al. Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain. J Pharm Sci. 2009 Oct;98 (10) :3509-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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