Succinimide

Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent[1][2].

Product Specifications

CAS Number

[123-56-8]

Product Name Alternative

Pyrrolidine-2,5-dione

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Others

Assay Protocol

https://www.medchemexpress.com/succinimide.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC(CC1)=O

Molecular Formula

C4H5NO2

Molecular Weight

99.09

Precautions

H302, H315, H319, H335

References & Citations

[1]Chu GC, et al. Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures. Pharm Res. 2007 Jun;24 (6) :1145-56. |[2]Yan B, et al. Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain. J Pharm Sci. 2009 Oct;98 (10) :3509-21.