UAMC00039 (dihydrochloride)

UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.

Product Specifications

CAS Number

[697797-51-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/UAMC00039_dihydrochloride.html

Purity

99.49

Solubility

DMSO : ≥ 150 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N1CCCCC1)[C@@H](N)CCNCC2=CC=C(Cl)C=C2.[H]Cl.[H]Cl

Molecular Formula

C16H26Cl3N3O

Molecular Weight

382.76

Precautions

H302, H315, H319, H335

References & Citations

[1]Maes MB, et al. In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII. Adv Exp Med Biol. 2006;575:73-85.|[2]Maes MB, et al. Dipeptidyl peptidase II and leukocyte cell death. Biochem Pharmacol. 2006 Jun 28;72 (1) :70-9.