Methyl 2- (7-hydroxy-2-oxo-2H-chromen-4-yl) acetate

Methyl 2- (7-hydroxy-2-oxo-2H-chromen-4-yl) acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection[1][2][3].

Product Specifications

CAS Number

[15991-13-6]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/methyl-2-7-hydroxy-2-oxo-2h-chromen-4-yl-acetate.html

Concentration

10mM

Purity

97.39

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

O=C1OC(C=C(O)C=C2)=C2C(CC(OC)=O)=C1

Molecular Formula

C12H10O5

Molecular Weight

234.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Nascimento JSD, et al. Mapping the Biotransformation of Coumarins through Filamentous Fungi. Molecules. 2019 Sep 29;24 (19) .|[2]Lizzul-Jurse A, et al. Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry. Org Biomol Chem. 2016 Aug 10;14 (32) :7777-91.|[3]Giovannini G, et al. Coumarin-based, switchable fluorescent substrates for enzymatic bacterial detection. Talanta. 2018 Oct 1;188:448-453.