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Fmoc-VAP-MMAE

Product Specifications

UNSPSC Description

Fmoc-VAP-MMAE is a agent-linker conjugates for ADC. Fmoc-VAP-MMAE consists of an ADC linker and a tubulin inhibitor MMAE (HY-15162), with a protective Fmoc group[1].

Target Antigen

Drug-Linker Conjugates for ADC

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fmoc-vap-mmae.html

Solubility

DMSO : 75 mg/mL (ultrasonic)

Smiles

O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](C)NC([C@H](C(C)C)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O)=O)=O)=O)=O)=O

Molecular Weight

1259.57

References & Citations

[1]Jackson David Y et al. Novel antibody-drug conjugates and related compounds, compositions, and methods of use. Patent. WO2016064749.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-148339/Fmoc-VAP-MMAE-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-148339/

Clinical Information

No Development Reported

CAS Number

1912408-91-3

Available Sizes

Curated Selection

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