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3α-Hydroxysteroid Dehydrogenase, Microorganism

3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism[1].

Product Specifications

CAS Number

[9028-56-2]

Product Name Alternative

3α-HSD

UNSPSC

12352204

Hazard Statement

H334

Target

Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/3α-hydroxysteroid-dehydrogenase-microorganism.html

Purity

95

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

[3a-HydroxysteroidDehydrogenase,Microorganism]

Precautions

H334

References & Citations

[1]Anne Z Steiner, et al. 3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism. J Clin Endocrinol Metab. 2008 Apr;93 (4) :1298-303.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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