QN523
Product Specifications
UNSPSC Description
QN523 is a novel scaffold with agent-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 induces apoptosis and autophagy. QN523 can be used in research of cancer[1].
Target Antigen
Apoptosis; Autophagy
Type
Reference compound
Related Pathways
Apoptosis;Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qn523.html
Solubility
DMSO : ≥ 16.67 mg/mL
Smiles
O=C(C1=NC=CN=C1)NC2=CC=CC3=CC=CN=C32
Molecular Weight
250.26
References & Citations
[1]Kuang Y, et, al. Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer. J Med Chem. 2022 Apr 28;65(8):6133-6156.|[2]Kuang Y, et, al. Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer. J Med Chem. 2022 Apr 28;65(8):6133-6156.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148255/QN523-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148255/QN523-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
878581-60-3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2074051-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Farnesyl Diphosphate Synthase (FDPS)
Ask
View Details 
MBS2074051-02 0.2 mL
APC/CY7-Linked Polyclonal Antibody to Farnesyl Diphosphate Synthase (FDPS)
Ask
View Details MBS2074051-03 0.5 mL
APC/CY7-Linked Polyclonal Antibody to Farnesyl Diphosphate Synthase (FDPS)
Ask
View Details MBS2074051-04 1 mL
APC/CY7-Linked Polyclonal Antibody to Farnesyl Diphosphate Synthase (FDPS)
Ask
View Details MBS2074051-05 5 mL
APC/CY7-Linked Polyclonal Antibody to Farnesyl Diphosphate Synthase (FDPS)
Ask
View Details MBS2074051-06 5x 5 mL
APC/CY7-Linked Polyclonal Antibody to Farnesyl Diphosphate Synthase (FDPS)
Ask
View Details