QN523
Product Specifications
UNSPSC Description
QN523 is a novel scaffold with agent-like properties, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines. QN523 induces apoptosis and autophagy. QN523 can be used in research of cancer[1].
Target Antigen
Apoptosis; Autophagy
Type
Reference compound
Related Pathways
Apoptosis;Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qn523.html
Solubility
DMSO : ≥ 16.67 mg/mL
Smiles
O=C(C1=NC=CN=C1)NC2=CC=CC3=CC=CN=C32
Molecular Weight
250.26
References & Citations
[1]Kuang Y, et, al. Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer. J Med Chem. 2022 Apr 28;65(8):6133-6156.|[2]Kuang Y, et, al. Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer. J Med Chem. 2022 Apr 28;65(8):6133-6156.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148255/QN523-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148255/QN523-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
878581-60-3
Available Sizes
Curated Selection
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