Bisindolylmaleimide VII
Bisindolylmaleimide VII is a potent inhibitor of calmodulin with high affinity for calmodulin (Kd=186.2 nM) . Bisindolylmaleimide VII is used to study the role of calmodulin in cancer, neurodegenerative diseases, and muscle dysfunction[1].
Product Specifications
CAS Number
137592-47-3
UNSPSC
12352005
Target
Calmodulin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer; Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/bisindolylmaleimide-vii.html
Smiles
O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CN(CCCN5CCNCC5)C6=C4C=CC=C6)NC3=O
Molecular Formula
C27H27N5O2
Molecular Weight
453.54
References & Citations
[1]Sosa-Peinado, et al. Bisindolylmaleimides new ligands of CaM Protein. Molecules 27.21 (2022) : 7161.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
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