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FAK inhibitor 2

Product Specifications

UNSPSC Description

FAK inhibitor 2 is a potent focal adhesion kinase (FAK) inhibitor with an IC50  of 0.07 nM, with antitumor and anti-angiogenesis activities[1].

Target Antigen

FAK

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fak-inhibitor-2.html

Purity

98.16

Solubility

DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C(NC)C(C=CC=C1)=C1NC2=C(C(F)(F)F)C=NC(NC3=CC=C(C(N4CCN(C(SCCN(C)C)=S)CC4)=O)C=C3)=N2

Molecular Weight

646.75

References & Citations

[1]Su Y, et al. Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities. Eur J Med Chem. 2019 May 18;177:32-46.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-128580/FAK-inhibitor-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-128580/FAK-inhibitor-2-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2354405-14-2

Available Sizes

Curated Selection

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