PROTAC α-synuclein degrader 3
PROTAC α-synuclein degrader 3 (Compound 5) is a selective α-synuclein PROTAC degrader. PROTAC α-synuclein degrader 3 can promote the ubiquitination and degradation of α-synuclein. PROTAC α-synuclein degrader 3 can be used for Parkinson's disease research (Pink: target protein ligand ; Black: linker; HY-133302; Blue: E3 ligase VHL ligand (HY-112078) ).
Product Specifications
CAS Number
2412273-77-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTACs; α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling; PROTAC
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/protac-α-synuclein-degrader-3.html
Purity
99.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CNC(C=C1)=CC=C1C2=NC3=C(S2)C=C(OCCOCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)C[C@@H](O)C4)=O)=O)C=C3
Molecular Formula
C51H68N6O11S2
Molecular Weight
1005.25
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein
Available Sizes
Frequently Asked Questions
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