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BI 224436

Product Specifications

UNSPSC Description

BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC50 values of less than 15 nM against different HIV-1 laboratory strains.

Target Antigen

HIV; HIV Integrase

Type

Reference compound

Related Pathways

Anti-infection;Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/BI-224436.html

Purity

99.74

Solubility

DMSO : ≥ 50 mg/mL

Smiles

CC1=C([C@@H](C(O)=O)OC(C)(C)C)[C@@]([C@@]2=CC=C3C4=C2N=CC=C4CCO3)=C5C(C=CC=C5)=N1

Molecular Weight

442.51

References & Citations

[1]Fenwick C, et al. Preclinical profile of BI 224436, a novel HIV-1 non-catalytic-site integrase inhibitor. Antimicrob Agents Chemother. 2014 Jun;58(6):3233-44.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-18595/BI-224436-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-18595/BI-224436-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

1155419-89-8

Available Sizes

Curated Selection

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