15-Deoxy-Δ12,14-prostaglandin A1
15-Deoxy-Δ12,14-prostaglandin A1 is a deoxyanalog of prostaglandins that inhibits NF-κB signaling and induces apoptosis. 15-Deoxy-Δ12,14-prostaglandin A1 inhibits TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecule (CAM) and avoids monocyte arrest[1].
Product Specifications
CAS Number
573951-20-9
Product Name Alternative
SC-39026; Declaben
UNSPSC
12352211
Hazard Statement
H225-H319-H336
Target
Apoptosis; NF-κB
Type
Reference compound
Related Pathways
Apoptosis; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/15-deoxy-12-14-prostaglandin-a1.html
Solubility
10 mM in DMSO
Smiles
OC(CCCCCC[C@@H]1/C(C=CC1=O)=C\C=C\CCCCC)=O
Molecular Formula
C20H30O3
Molecular Weight
318.45
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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