ABT-046
ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of both 8 nM against human and mouse DGAT-1[1].
Product Specifications
CAS Number
1031336-60-3
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/abt-046.html
Purity
98.57
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
NC1=C(C2=CC=C([C@H]3CC[C@H](CC(O)=O)CC3)C=C2)C=NC4=CC=NN41
Molecular Formula
C20H22N4O2
Molecular Weight
350.41
References & Citations
[1]Yeh VS, et al. Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of Acyl-CoA: Diacylglycerol acyltransferase 1. J Med Chem. 2012 Feb 23;55 (4) :1751-1757.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: B-E16]](https://cdn.genprice.uk/products/937/68dd189d061270361e8fcf19/imageurl/am31227fc-n.webp)
AM31227FC-N 1 mL (100 Tests)
CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: B-E16]
Sign In for Pricing
View Details 