Uridine 5'-monophosphate (disodium salt)

Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea[1][2][3].

Product Specifications

CAS Number

[3387-36-8]

Product Name Alternative

5'-Uridylic acid (disodium salt)

UNSPSC

12352005

Hazard Statement

H315, H317, H319, H335, H360

Target

Apoptosis; Cholinesterase (ChE) ; Endogenous Metabolite; Potassium Channel

Type

Oligonucleotides

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Uridine_5_acute_-monophosphate_disodium_salt.html

Purity

99.90

Solubility

H2O : ≥ 50 mg/mL

Smiles

O[C@@H]([C@H](N(C1=O)C=CC(N1)=O)O2)[C@H](O)[C@H]2COP(O[Na])(O[Na])=O

Molecular Formula

C9H11N2Na2O9P

Molecular Weight

368.14

Precautions

H315, H317, H319, H335, H360

References & Citations

[1]Li G, et al. Uridine/UMP metabolism and their function on the gut in segregated early weaned piglets. Food Funct. 2019 Jul 17;10 (7) :4081-4089.|[2]Mehmet Cansev, et al. Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils. Brain Res. 2005 Oct 5;1058 (1-2) :101-8.|[3]Irina B Krylova, et al. The cardioprotective effect of uridine and uridine-5'-monophosphate: the role of the mitochondrial ATP-dependent potassium channel. Exp Gerontol. 2006 Jul;41 (7) :697-703.