PIKfyve-IN-1
Product Specifications
UNSPSC Description
PIKfyve-IN-1 is a highly potent and cell-active chemical probe that inhibits phosphatidylinositol-3phosphate 5-kinase (PIKfyve) with IC50 value of 6.9 nM. PIKfyve-IN-1 can be used for the research of PIKfyve in virology[1]. PIKfyve-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
PIKfyve
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/pikfyve-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)
Smiles
NC1=NC=C(CCC2)C(C3=C2NC4=C3C=C(C#CCN(C)C)C=C4)=N1
Molecular Weight
331.41
References & Citations
[1]David H Drewry, et al. Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses. J Med Chem
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151473/PIKfyve-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151473/PIKfyve-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2857982-26-2
Available Sizes
Curated Selection
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