STAT5-IN-2
STAT5-IN-2 is a STAT5 inhibitor, extracted from reference 1, example 17f. STAT5-IN-2 has potent antileukemic effect[1].
Product Specifications
CAS Number
[2111834-61-6]
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/STAT5-IN-2.html
Purity
99.08
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(CCN1CCOC2=CC(C=CN3)=C3C=C2)(C)C4=C1C=CC(C5=CC=CN=C5)=C4
Molecular Formula
C26H27N3O
Molecular Weight
397.51
References & Citations
[1]Ludovic Juen, et al. New Inhibitor Targeting Signal Transducer and Activator of Transcription 5 (STAT5) Signaling in Myeloid Leukemias. J Med Chem. 2017 Jul 27;60 (14) :6119-6136.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT5
Available Sizes
Curated Selection
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