Atuveciclib S-Enantiomer

Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is a potent and selective CDK9 inhibitor, which inhibits CDK9/CycT1 with an IC50 of 16 nM.

Product Specifications

CAS Number

[2250279-81-1]

Product Name Alternative

BAY-1143572 S-Enantiomer

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BAY-1143572_S-Enantiomer.html

Purity

99.38

Solubility

DMSO : ≥ 113 mg/mL

Smiles

N=[S@@](CC1=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=CC=C1)(C)=O

Molecular Formula

C18H18FN5O2S

Molecular Weight

387.43

References & Citations

[1]Lücking U, et al. Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer. ChemMedChem. 2017 Nov 8;12 (21) :1776-1793.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-06324CL1 0.1 mL

Rabbit Polyclonal SMAGP Antibody [CoraFluor 1]

Ask

View Details

bsm-62160R-PE-Cy7 100 µL

DDX17 Recombinant Antibody, PE-Cy7 Conjugated

Ask

View Details

GTR15157017 1 Vial

Lentiviral human KHSRP shRNA (UAS) - Lentiviral human KHSRP shRNA (UAS, GFP) (100)

Ask

View Details

A18903-50 50 mg

3-Hydroxydecanoic acid 50mg

Ask

View Details