ω-Conotoxin CVID

Product Specifications

CAS Number

[247207-64-3]

UNSPSC Description

ω-Conotoxin CVID (Leconotide, AM336, CNSB004) blocks neuronal voltage sensitive calcium channel[1].

Target Antigen

Calcium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@]1([H])NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC[C@]2([H])NC([C@@](CSSC[C@H](NC([C@@H](NC(CNC([C@@H](NC([C@](NC(CNC([C@@H](NC([C@](NC([C@@H](NC(CNC([C@@H](NC2=O)CO)=O)=O)CO)=O)([H])CSSC1)=O)CO)=O)=O)([H])[C@H](O)C)=O)C(C)C)=O)=O)CCCNC(N)=N)=O)C(N)=O)([H])NC([C@@H](NC3=O)CC(O)=O)=O)=O)N)=O)CCCCN)=O)CO)=O)CCCCN)=O)=O)C)=O)CCCCN)=O)=O)CO)=O)CCCCN)=O)CC(C)C)=O)CCSC)N[C@H]3CC4=CC=C(C=C4)O

Molecular Weight

2756.23

References & Citations

[1]Anton Kolosov, et al. CNSB004 (Leconotide) Causes Antihyperalgesia Without Side Effects When Given Intravenously: A Comparison with Ziconotide in a Rat Model of Diabetic Neuropathic Pain.Pain Med. 2010 Feb;11(2):262-73.