(-) -Dihydroguaiaretic acid
(-) -Dihydroguaiaretic acid is a Lipoxygenase inhibitor that has antioxidant activity. (-) -Dihydroguaiaretic acid inhibits the oxidation of unsaturated fatty acids and removes free radicals. (-) -Dihydroguaiaretic acid also has anticancer activity with an IC50 value of 7.49 μM (A549 cells) [1][2].
Product Specifications
CAS Number
124649-78-1
UNSPSC
12352005
Target
Lipoxygenase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/minus-dihydroguaiaretic-acid.html
Purity
98.79
Solubility
10 mM in DMSO
Smiles
COC(C=C1C[C@@H](C)[C@H](C)CC2=CC(OC)=C(C=C2)O)=C(C=C1)O
Molecular Formula
C20H26O4
Molecular Weight
330.42
References & Citations
[1]Yamauchi S, et al. Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid. Biosci Biotechnol Biochem. 2008 Nov;72 (11) :2981-6. |[2]Davis R A, et al. Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum[J]. Bioorganic & medicinal chemistry, 2009, 17 (3) : 1387-1392.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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