PI3Kα-IN-11
PI3Kα-IN-11 is a potent PI3Kα inhibitor with anticancer activity[1].
Product Specifications
CAS Number
[300803-79-6]
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kα-in-11.html
Purity
95.35
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC2=C(C(O)=C1C(NCC3=CC=CC=C3)=O)C=CC=C2
Molecular Formula
C17H14N2O3
Molecular Weight
294.30
References & Citations
[1]Sabbah DA, et al.N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα) . Bioorg Med Chem. 2012 Dec 15;20 (24) :7175-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα
Available Sizes
Curated Selection
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