PI3Kα-IN-11
Product Specifications
UNSPSC Description
PI3Kα-IN-11 is a potent PI3Kα inhibitor with anticancer activity[1].
Target Antigen
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kα-in-11.html
Solubility
DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C1NC2=C(C(O)=C1C(NCC3=CC=CC=C3)=O)C=CC=C2
Molecular Weight
294.30
References & Citations
[1]Sabbah DA, et al.N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα). Bioorg Med Chem. 2012 Dec 15;20(24):7175-83.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153915/PI3Kα-IN-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153915/PI3Kα-IN-11-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
300803-79-6
Available Sizes
Curated Selection
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