PI3Kα-IN-11

PI3Kα-IN-11 is a potent PI3Kα inhibitor with anticancer activity[1].

Product Specifications

CAS Number

[300803-79-6]

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3kα-in-11.html

Purity

95.35

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1NC2=C(C(O)=C1C(NCC3=CC=CC=C3)=O)C=CC=C2

Molecular Formula

C17H14N2O3

Molecular Weight

294.30

References & Citations

[1]Sabbah DA, et al.N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα) . Bioorg Med Chem. 2012 Dec 15;20 (24) :7175-83.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kα

Available Sizes

Curated Selection

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